Peptide Active Data Details
Basic Peptide Information
DICL ID
DICL_Pep_04851
Ion Channel
Sodium channel protein type 5 subunit alpha
Peptide Function
Inhibitor
Gene Name
SCN5A
Activity Data (nM)
IC50
90 nM
Ki
Not available
EC50
Not available
Kd
Not available
Biologically Active
Not specified
Sequence Information
Peptide Sequence
YCQKWMWTCDSERKCCEGMVCRLWCKKKLW
Peptide UniProt Accession
UniParc
Not available
Peptide Synonyms/Alias
[CHEMBL3318132; CHEMBL4224739; BDBM50051073]
Peptide Species
Thrixopelma pruriens (Peruvian green velvet tarantula)
Peptide Name
Beta/omega-theraphotoxin-Tp2a
CAS Number
484598-36-9
Experimental Conditions
pH
Extracellular solution: pH 7.4/Intracellular solution: pH 7.3
Holding Potential (mV)
−125 to −20 mV
Temperature
~22 °C
Test Method
Patch-clamping
Test Species
Not specified
Binding Information
Binding Site
Extracellular domain
Binding Site Residue
Not specified
Ion Channel Information
Gene Abbreviation (ABB)
VGSCs
Ion Channel UniProt Accession
Source Organism
Homo sapiens (Human)
References & Disease Information
Disease
Not specified
PubChem CID
URL
Not available
PMID
Patent
Not available